May 25, 2011

Urological outcome after myelomeningocele: 20 years of follow-up.

Urological outcome after myelomeningocele: 20 years of follow-up.: "


Urological outcome after myelomeningocele: 20 years of follow-up.

BJU Int. 2011 Mar;107(6):994-9

Authors: Thorup J, Biering-Sorensen F, Cortes D

• To evaluate the urological outcome in a long-term follow-up of individuals with myelomeningocele and relate the findings obtained to urodynamic variables in childhood.

PMID: 20860652 [PubMed - indexed for MEDLINE]
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May 11, 2011

Detrusor Arreflexia as an End Stage of Neurogenic Bladder in HAM/TSP?

Detrusor Arreflexia as an End Stage of Neurogenic Bladder in HAM/TSP?: "


Detrusor Arreflexia as an End Stage of Neurogenic Bladder in HAM/TSP?

Case Report Med. 2011;2011:289389

Authors: Tannus M, Tanajura D, Sundberg MA, Oliveira P, Castro N, Santos AM

The HTLV-1 virus is a known agent involved in the development of HAM/TSP. Past studies have typically observed patients with autonomic dysfunction consisting of detrusor overactivity and detrusor-sphincter dyssynergia, with the occasional observation of underactive detrusor or detrusor arreflexia. However, studies have not yet evaluated the progression of neurogenic bladder over time. In this paper, we describe a HAM/TSP patient with the initial development of overactive detrusor, and subsequent development of detrusor arreflexia. Given a paucity of studies characterizing the effects of HTLV-1 on the autonomic nervous system, particularly aspects controlling continence, this patient's clinical course may represent one type of end point for patients with HAM/TSP and neurogenic bladder. Further cohort or case-series studies, with particular emphasis on the progression of neurogenic bladder, are needed to evaluate the significance of this described case in relation to typical disease progression patterns.

PMID: 21541226 [PubMed - in process]
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May 5, 2011

Acute urinary retention in a 23-year-old woman with mild encephalopathy with a reversible splenial lesion: a case report.

Acute urinary retention in a 23-year-old woman with mild encephalopathy with a reversible splenial lesion: a case report.: "


Acute urinary retention in a 23-year-old woman with mild encephalopathy with a reversible splenial lesion: a case report.

J Med Case Reports. 2011 Apr 20;5(1):159

Authors: Kitami M, Kubo SI, Nakamura S, Shiozawa S, Isobe H, Furukawa Y

ABSTRACT: INTRODUCTION: Patients with clinically mild encephalitis/encephalopathy with a reversible splenial lesion present with relatively mild central nervous system disturbances. Although the exact etiology of the condition remains poorly understood, it is thought to be associated with infective agents. We present a case of a patient with mild encephalitis/encephalopathy with a reversible splenial lesion, who had the unusual feature of acute urinary retention. Case presentation A 23-year-old Japanese woman developed mild confusion, gait ataxia, and urinary retention seven days after onset of fever and headache. Magnetic resonance imaging demonstrated T2 prolongation in the splenium of the corpus callosum and bilateral cerebral white matter. These magnetic resonance imaging abnormalities disappeared two weeks later, and all of the symptoms resolved completely within four weeks. Except for the presence of acute urinary retention (due to underactive detrusor without hyper-reflexia), the clinical and radiologic features of our patient were consistent with those of previously reported patients with mild encephalitis/encephalopathy with a reversible splenial lesion. To the best of our knowledge, this is the first report of acute urinary retention recognized in a patient with mild encephalitis/encephalopathy with a reversible splenial lesion. Conclusion Our findings suggest that mild encephalitis/encephalopathy with a reversible splenial lesion can be associated with impaired bladder function and indicate that acute urinary retention in this benign disorder should be treated immediately to avoid bladder injury.

PMID: 21507219 [PubMed - as supplied by publisher]
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