March 18, 2013

Investigation into neurogenic bladder in arthrogryposis multiplex congenita.

Investigation into neurogenic bladder in arthrogryposis multiplex congenita.:
Investigation into neurogenic bladder in arthrogryposis multiplex congenita.
J Pediatr Urol. 2013 Mar 10;
Authors: Arantes de Ara├║jo L, Ferraz de Arruda Musegante A, de Oliveira Damasceno E, Barroso U, Badaro R
Abstract

OBJECTIVE: During the follow-up of children who had been diagnosed with arthrogryposis multiplex congenita (AMC), it was noted that some were experiencing dysfunctional voiding. Further investigation into these cases led to a diagnosis of neurogenic bladder. Few studies have investigated the relationship between AMC and neurogenic bladder, this being the first to describe the clinical characteristics of neurogenic bladder among these patients. METHODS: A series of 26 cases were obtained from the electronic medical records of patients with AMC who were admitted to Hospital Sarah in Salvador between 1994 and 2007. The patients had all been diagnosed with neurogenic bladder through clinical symptoms, lower urinary tract exams, and urodynamic findings. RESULTS: There was urinary incontinence in 21 patients (81%), and 50% had a history of urinary tract infections. Renal function was altered in 4 patients (15%) and normal in 22 (85%). In the urodynamic study, 14 patients (64%) had detrusor overactivity and 6 (27%) had underactivity. CONCLUSION: Patients with AMC may show changes in the urinary tract, including neurogenic bladder. It is mandatory to study these symptomatic children with urinary disorders.


PMID: 23491981 [PubMed - as supplied by publisher]

March 13, 2013

Unravelling the underactive bladder: a role for TRPV4?

Unravelling the underactive bladder: a role for TRPV4?:
Unravelling the underactive bladder: a role for TRPV4?
BJU Int. 2013 Feb;111(2):353-4
Authors: Everaerts W, De Ridder D
PMID: 23476938 [PubMed - in process]